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This ground-breaking digital tool offers the best of both worlds: automated computational QSAR using one of the largest chemical toxicology databases available, combined with the reliability of read across. REACHAcross™ works by building large networks of chemicals based on properties such as molecular structure and health endpoint interactions.
Using advanced machine-learning techniques, it predicts 8 required endpoints for REACH submissions. Users can produce Toxicology Assessment Reports for 6 key human health endpoints, including skin sensitization, acute dermal irritation, acute eye irritation, acute oral toxicity, acute dermal toxicity, mutagenicity and 2 key ecotoxicity endpoints of acute aquatic toxicity and chronic aquatic toxicity.
REACHAcross™ is a highly advanced artificial intelligence tool that provides a digital alternative to animal testing and offers a new, accurate and rapid way to comply with REACH.
Our sophisticated computational algorithm builds large networks of chemicals based on properties such as molecular structure and hazard endpoint interactions. The REACHAcross ™ system uses curated data from multiple, widely accepted public sources.
Using advanced machine-learning and complex mathematical algorithms, the system is able to accurately assess health and environmental impacts for the chemical entered with the certainty of an animal test and sensitivities of 80% across endpoints. The algorithms include a prediction of hazard endpoint potency that correlates to a GHS Hazard Classification Category.
A REACH dossier compliant Toxicology Assessment Report is generated for up to 8 key endpoints including: Skin Sensitization, Acute Dermal Irritation, Acute Eye Irritation, Acute Oral Toxicity, Acute Dermal Toxicity, Mutagenicity, Acute Aquatic Toxicity and Chronic Aquatic Toxicity. Additional endpoints will be added.
Data from the REACHAcross™ Toxicology Assessment Report can be used to populate IUCLID, the European Chemicals Agency ‘s (ECHA) formal reporting tool for REACH compliance.
Access a sample REACHAcross™ Toxicology Assessment Report.
Whether you work for a manufacturer, are a consulting toxicologist, filing independently or through a Substance Information Exchange Forum (SIEF), REACHAcross™ can help you produce REACH dossier compliant toxicology reports with speed and precision. REACHAcross™ is a highly advanced artificial intelligence tool that saves you time and money by replacing the need for costly animal testing and the expense of hiring additional expert support. Unlike conventional read-across, REACHAcross™ provides a predictive accuracy for 6 required human health endpoints and 2 ecotoxicity end points. Use UL REACHAcross™ to produce your REACH compliant Toxicology Assessment Reports , or use to supplement your conventional read-across arguments to provide additional weight of evidence at minimal cost.
REACHAcross™ enables product stewards/regulatory professionals to fill 8 required REACH endpoints with the use of a digital tool so you can assemble and submit dossiers for REACH compliance, including a prediction of the required GHS Classification and Category. If your company lacks internal toxicology resources, this tool can help you rapidly determine and cost-effectively generate data, thereby minimizing the amount of external consulting costs.
Optimize your turnaround times and client satisfaction with REACHAcross™, a highly advanced artificial intelligence tool that enables you to manage more chemicals with higher confidence and consistency of results. In addition to increasing through-put and capacity, the tool is validated to OECD Principles and calculates uncertainty probability for producing a hazard, increasing your level of confidence. Use REACHAcross™ to give your clients fast access to REACH complaint Toxicology Assessment Report s , while reducing your outsourcing and animal testing costs.